Journal: Brazilian Journal of Medical and Biological Research
Article Title: Improvement of indirect immunofluorescence technique to detect antineutrophil cytoplasmic antibodies and its impact on test positivity rate
doi: 10.1590/1414-431X2023e12636
Figure Lengend Snippet: Positivity of antineutrophil cytoplasmic antibodies (ANCA) tests performed at diagnosis. This analysis includes all study participants that had ANCA tests performed at diagnosis. The positivity rate was 32.0% (10/31) for indirect immunofluorescence (IIF)-ANCA tests performed at the Immuno-Rheumatology laboratory ( A ), 75.0% (9/12) for IIF-ANCA tests performed by other laboratories ( B ), and 72.8% (8/11) for ELISA tests performed at diagnosis by other laboratories ( C ). Analyses were performed with Fisher's exact test.
Article Snippet: MPO-ANCA and PR3-ANCA were tested using a third generation ELISA kit (Euroimmun, Germany).
Techniques: Immunofluorescence, Enzyme-linked Immunosorbent Assay